i26 (IgY Max®) has been studied in numerous universities, hospitals and research centers around the world over the last 20 years, from Harvard Medical School to the U.S. Army Research Institute of Environmental Medicine. 
What is ​i26 Hyperimmune Egg?
Made from specific hyperimmune egg powder, IgY Max® is a polyvalent (immunity against different strains of a microorganism) IgY product that provides a new approach to modifying the microbiome. By acting as a barrier protector, IgY Max® supports the body’s natural detoxification process, promotes a proper inflammatory response, supports a proper flora balance and promotes the growth of beneficial gut bacteria to deliver the benefits of passive immunity for optimal gut health.

How does ​i26 Hyperimmune Egg work?
i26 Hyperimmune Egg contains strain-specific antibodies against 26 common human-relevant pathogens to:
  • Support digestive tract lining 
  • Promote proper microbial adhesion 
  • Support immune system health 
  • Support the body’s natural defenses​
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Just like weeds in a garden, opportunistic bacteria compete with beneficial flora, taking up vital nutrients needed to survive. By reducing the occurrence of potentially harmful microbes in the intestinal tract, IgY Max® helps promote the attachment of beneficial bacteria to improve microbial diversity, thus improving gastrointestinal function and overall wellbeing
Results of an open label pilot study revealed that 8 weeks of IgY Max® supplementation significantly increased microbial diversity and improved biomarkers of gut wall integrity in subjects reporting mild to moderate GI complaints.

1.
IgY Max® contains strain-specific antibodies against 26 human-relevant bacteria to promote mucosal immunity by inhibiting adhesion of non-beneficial bacteria in the digestive tract. 1,7,8

2.
IgY Max® promotes the growth of healthy bacteria by reducing competition for space in the gut. 2

3.
IgY Max® helps promote a normal inflammatory response while optimizing healthy digestive function by regulating inflammatory cytokines (type of protein made by certain cells that effect the immune system). 2(10),7(2)

4.
IgY Max® promotes GI health:
  • Reduce non-beneficial bacteria adherence 8(6)
  • Increase gut wall integrity 2(11)
  • ​Improve bowel function 5(52).8(6)

5.
IgY offers additional benefits compared to IgG4 (type of antibody found in the immune system) : 
  • 3-5X higher immunogenicity 7(1) 
  • Does not increase inflammatory cytokines 4(6) 
  • 20X higher immunoglobulin concentration per unit 1(12)

6.
IgY Max® is self-affirmed GRAS (Generally Recognized As Safe)​ and holds a Master Food Additive file number. 3
1 See, D. MD. Draft. University of California, Irvine. Division of infectious diseases- department of immunology. 1998. 2 Ambekar R. Effect of a nutritious drink fortified with immune egg in improving the weight and enhancing the well-being of subjects. Unpublished study.1998.3 Artis, A. M. Food Additive Master File No. 000595. Food and Drug Administration. May 17, 1996. 4 Dias da Silva W, Tambourgi D. Veterinary Immunology and Immunopathology. 2010;135(3-4):173-180. doi:10.1016/j.vetimm.2009.12.011. 5 Jacoby, H. Moore, G. Wnorowski, G. Journal of Nutraceuticals, Functional & Medical Foods, 2001;3(2):47-53. 6 Miles, Laura. Effects of Hyperimmune Eggs on HSCRP Levels: Results of a private clinical trial. Unpublished study. 7 Rahman, S., Nguyen, S., Jr., F., Umeda, K., & Kodama, Y. (2013). Human Vaccines & Immunotherapeutics, 9(5), 1039-1048. doi:10.416/hv.23383. 8 Chalghoumi, R., Théwis, A., Beckers, Y., Marcq, C., Portetelle, D., & Schneider, Y. (2009). Foodborne Pathogens and Disease, 6(5), 593-604. doi:10.1089/fpd.2008.0258